** Key** Chapter 20 Review Questions

  1. The Centers for Disease Control and Prevention (CDC)
  2. Steps: 1) Prepare for field work, 2) establish existence of outbreak, 3) verify cases, 4) establish case definition and search for additional cases, 5) descriptive epi, 6) develop hypotheses, 7) evaluate hypotheses, 8) refine hypotheses and conduct additional studies, 9) implement control and prevention measures, 10) communicate findings. See Chapter 20 for
  3. (b) a “time variable”
  4. (a) the number of cases
  5. (a) outlier
  6. Either via a surveillance system or a case or health care worker notifying the agency directly.
  7. Surveillance systems are organizations set up to routinely collect and analyzed public health outcomes.
  8. No, they often miss cases and lack information on important contributors to occurrence.
  9. No, it can merely indicate an increase in reporting.
  10. An astute pharmacist noted an increase in the number of requests for a drug used to treat Pneumocystis pneumonia, and that these requests were coming from atypical types of patients.
  11. The decision to mount an investigation depends on: a) The ability to confirm a greater than expected number of cases, b) the scale and severity of the outbreak, c) whether a identifiable subgroup is disproportionally effected, d) the potential for spread, e) political and public relations considerations, f) availability of resources
  12. Goals of investigations: a) assess the extent of the outbreak, b) reduced the future number of cases, c) prevent future occurrence, d) identify new disease syndromes, e) identify new causes, f) assess the efficacy of current prevention strategies, g) address liability and legal concerns, h) train epidemiologists, i) public relations and public education.
  13. “Define the problem” means to confirm the cases and show that an outbreak truly exists.
  14. Occurrence is described by person, place, and time factors.
  15.  control mechanisms.
  16. Hypotheses are tested with epidemiologic, laboratory, and environmental investigations.
  17. True.
  18. expected
  19. Examples of information biases: changes in reporting procedures or case definitions; fads and false alarms
  20. By increasing the number at risk with no real increase in the incidence proportion or rate. 
  21. Improved diagnostic procedures or increased awareness may cause an apparent increase in occurrence, when no real increase in occurrence is operating.
  22. A case definition is the standard criteria used to decide whether someone is a case.
  23. (a) case identification information (b) demographic information (c) clinical information (d) risk factor information (e) reporter information (f) denominator information
  24. (a) assess quality and completeness of information (b) learn about the extent of the outbreak (c) assess possible sources of exposure, mode of transmission, incubation period, (d) learn about agent, host, and environmental contributors (e) generate hypotheses about cause
  25. True (see p. 357, Figure 20.1)
  26. Incubation period = the time interval between invasion of the agent into the host’s body and the appearance of first signs or symptoms.
  27. (a) Pathogenicity of the agent, (b) level of exposure, (c) susceptibility of the host
  28. A hypothesis is a tentative explanation that accounts for a set of facts that can be tested by further investigation.
  29. disease process
  30. Information is reported to (a) the initial informants, (b) the local, state and federal agencies, and (c) community affected by the outbreak
  31. how and why.