CHAPTER 5: Case Definitions and Disease Classification

REVIEW QUESTIONS [Last update: 3/9/04]

�5.1 Case Definitions

What does an epidemiologist mean when he or she refers to a "case definition"? 
2
What general types of criteria can be used to construct a case definition?
3 T/F: Case definitions must be applied uniformly. 
Provide examples of person, place, and time criteria that can be incorporated into an epidemiologic case definition.
5 T/F: Case definitions may evolve over time as additional information is learned about the pathology of the disease. 
6 What does an epidemiologist mean when he or she refers to a "Chinese menu" case definition.
7 What are some of the benefits derived from applying a uniform case definition for a vague syndrome like Chronic Fatigue Syndrome.
8 Do you think Major Criteria #2 for for Chronic Fatigue Syndrome as described in Table 5.1, p. 114 ("other conditions that produce similar symptoms excluded")  was included in order to increase the specificity or sensitivity of the case definition?
9 Discuss how the AIDS case definition has evolved over time. 
10
Does a person have to have symptoms to qualify as an AIDS case? (Explain why or why not.)
11 What three [qualitative] levels of certainty might be attached to a case definition?
12 Confirmed cases usually require _____________________.
13 List the two general ways a person may qualify as an AIDS case.

�5.2 ICD

1 What does ICD stand for? 
2 What is the current version of the ICD? 
3 How many major categories of disease are in ICD-9?
4 In ICD-9, is there a  major category for injuries and poisonings?
5 Without knowing anything about the specific condition, what can be said about ICD 250.61 relative to ICD 250. 
6 Is ICD-9 still in use? 
7 What is an ICD-9 E-code? What is a V-code?
8 How is ICD9 organized?
9 Which of the following factors are used to group diseases? (check all that apply): a) similarities in cause b) pathogenesis c) anatomical location
10 T/F: There is a category for ill-defined conditions in ICD-9.

�5.3 ARTIFACTUAL FLUCTUATIONS

1 List factors that may cause an artifactual increase or decrease in reported rates of disease.
2
List factors that may cause an artifactual increase or decrease in the reported rates of death.
3
Why was there a dramatic increase in the rate of AIDS in 1993?  

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