CHAPTER 3: Infectious Disease Process

REVIEW QUESTIONS [last update: 12/3/03]

�3.1 The Infectious Disease Process

1   How does infection differ from contamination?
2   How does infection differ from infectious disease?
3   List the types of infectious disease agents, from largest to smallest.
4   Name the four types of reservoirs.
5   How does a case differ from a carrier?
6   What do you call an infectious disease in which the agent is shared by  humans and non-human animals?
7   List examples of inanimate objects that may serve as reservoirs.
8   How does a cyclozoonoses differ from a direct zoonosis?
9   How does a metazoonosis differ from a direct zoonosis?
10   What does the prefix sapro- mean?
11   List the 6 portals of entry and exit for infectious agents.
12   How does direct contact transmission differ from indirect contact transmission?
13   How does droplet transmission differ from droplet nuclei transmission?
14   How does a vector differ from a vehicle?
15   How does mechanical transmission differ from developmental transmission?
16   How does developmental transmission differ from propagative transmission?
17   Was the Broad Street pump cholera outbreak of 1854 (Chap 1) a common-vehicle spread or serial spread outbreak?
18   Does the common cold spread by a common-vehicle or serially?
19   How does knowledge of an agent's biological cycle help with its control?
20   How does understanding the natural history of a disease help with its control?
21   True of false?: Nonspecific inflammatory responses in the host (e.g., fever) are innate forms of immunity. 
22   The act of acquiring immunity is called _______________.
23   How does passive immunization differ active immunization.
24   Identify two forms of passive immunization.
25   Intentional exposure to an antigen in order to initiate an immune response is called _______________.
26   Generally speaking, do killed or modified live vaccines produce more sustained immune responses? Explain.
27   Cell mediated immune responses are mediated through biochemical cell proteins called _______________.
28   This type of immunocyte produces antibodies.
29   HIV selectively attacks this type of immunocyte.
30   B and T cells are types of  __________________.
31   What are two different reasons to study the infectious disease process?

�3.2 HERD IMMUNITY

1 Define herd immunity.
2 How does innate herd immunity differ from acquired herd immunity.
3 Provide an example of innate herd immunity.
4 Describe why the entire "herd" need not always be vaccinated in order to stem the progression of an epidemic.
5 In scenario 2 in Fig. 3.4 (p. 73), why is the incidence of infection 2 / 7 as opposed to 2 / 20.

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